What factors affect Markovnikov selection in hydroamination catalysis with metallacycle intermediates?
Answer:
The main factor in markinoz addition to any alkene is what adds first. Remember, the first step is the addition of an electophile and the formation of a carbocation intermediate. The positive charge goes on the more highly substituted carbon atom. In some of the reactions, the electrophile forms a ring. When this happens, the second step with attack from the opposite side, and since bond-breaking is ahead of bond-forming, the partial positive charge will go on the more highly substituted carbon atom. When looking at the transition state, the partially broken bond should go on the more substituted carbon.
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