Explain this ???
In bromination of phenol p-bromophenol is major product and in nitration o-nitrophenol is major product.Explain this ?
Answer:
Different mechanisms. Normally the electrophilic reagent stays away from the OH substituent just because of steric effects, favoring the para product. But some reagents can hydrogen-bond or somehow connect to the OH group, giving mainly the ortho product. A similar phenomenon is observed in the synthesis of salicylic acid, where CO2 is the electrophile. Nitration is pretty similar because the NO2(+) electrophile and CO2 are isoelectronic species.
More Questions and Answers:
Wnich burn hotter: steam or boiling water?
How do compounds form acids in solutions and what kinds of compounds tend to do so?
If 6 M of H2SO4 is substituted for 6 M HCl will more or less drops of 6 M H2SO4 be required for .....
How does changing the pH affect the rate of enzyme activity?
Is there a way to change a ketone to an alcohol in Organic Chemistry?
What is isomer?
Heres the following data for the unknown formula?
What is the structural formula? (chemistry)?
Why should the cork and the glass tubing be moistened with water?
Answer:
Different mechanisms. Normally the electrophilic reagent stays away from the OH substituent just because of steric effects, favoring the para product. But some reagents can hydrogen-bond or somehow connect to the OH group, giving mainly the ortho product. A similar phenomenon is observed in the synthesis of salicylic acid, where CO2 is the electrophile. Nitration is pretty similar because the NO2(+) electrophile and CO2 are isoelectronic species.
The answers post by the user, for information only, FunQA.com does not guarantee the right.
More Questions and Answers: