Laboratories that measure Capsaicin?

I'm trying to find out how much capsaicin is in certain peppers, charts give me vague ranges but i want to so how much capsaicin is in them precisely. Do you know of any labs that could measure the levels of capsaicin?

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To determine the amount of capsaicin in a pepper you would want to find a spectroscopic technique to determine concentration. Any technique that can shows an increase in intensity with increased amounts of capsaicin could theoretically be modeled to determine the [capsaicin] in each of your peppers.

The first thing that would needs to be done is purification. I looked up capsaicin and it appears as though it would absorb in the UV-vis region due to it's aromatic ring. If this is true then determining concentration would be easy.

So assuming you had purified your capsaicin, you could order some pure stuff from sigma aldrich or other chemical wholesaler, and then use UV vis spectroscopy to determine the extinction coefficient for it. You could probably even by-pass this step and find it in literature. I'm not sure though.

However, once you had the extinction coefficient you could measure the concentration of capsaicin in your peppers pretty easily using Beer's law (A = ebc). There is a problem though. This would be useful for comparing relative concentrations of capsaicin in peppers but might not be accurate in determing the actual amount of capsaicin in the peppers due to the loss of capsaicin that might occur during purification.

Regardless, I think this is a pretty common procedure for experimentally determing concentrations of small molecules and proteins in cell.

I hope this helps.

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